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No phaseCompletedAge-related condition

Imaging Biomarkers of the Effects of a Mixed Exercise Program (SarcoImage)

SarcoImage: Anatomical and Physiological Validation by Magnetic Resonance Imaging Biomarkers of the Effects of High Intensity Strenght Training and Myofascial Self-conditioning on Sarcopenia in Frail and Prefrail Elderly

Sponsor
University of Valencia (Academic or other)
Enrollment
60 enrolled
Conditions
Sarcopenia
Interventions
Mixed exercise program
Ages
older adults
Registry
NCT03834558

Full record on ClinicalTrials.gov

From the registry

The aim is quantify, correlate and establish the diagnostic and prognostic value of the variation of the image biomarkers obtained by magnetic resonance (muscle volume, morphological, biochemical and structural biomarkers) longitudinally in fragile or pre-frail elders with sarcopenia after a mixed physical training of strength and myofascial self-conditioning. This project is based on an, longitudinal, prospective, controlled, randomized, intervention study and blind for the researchers responsible for the study. 60 elderly with sarcopenia and frailty (Intervention Group, n=30; Control Group, n=30) will participate in the study. Intervention Group participants will perform 6-months mixed exercise program consisting in high-intensity strength training and self-myofascial conditioning. Data will be take trough 2 measurements that will be take place at baseline and post-intervention. Criteria of frailty, criteria of sarcopenia, sociodemographic, clinics, kinanthropometric, functional, nutritional and confusing variables will be evaluated. Moreover, magnetic resonance images will be…

Primary outcomes

  • Muscle volume
  • Bone volume
  • Relative volume of intramuscular fat
  • Extramuscular subcutaneous fat

History

  1. Last registry update

  2. Study completion

  3. Primary completion

  4. Registered

  5. Started

Papers citing this trial