No phaseCompletedAge-related condition
Skeletal Muscle as a Mediator of Exercise Induced Effects on Metabolism & Cognitive Function: Role for Myokines & miRNAs (Brain-Muscle)
- Sponsor
- Slovak Academy of Sciences (Government)
- Enrollment
- 30 enrolled
- Conditions
- Mild Cognitive Impairment; Alzheimer Disease; Parkinson Disease; Healthy Volunteers
- Interventions
- 3 months exercise intervention program
- Ages
- adults, older adults
- Registry
- NCT02253732
Full record on ClinicalTrials.gov
From the registry
The purpose of this study is to determine specific changes in muscle secretory profile (myokines, miRNA) in association with neurodegenerative disease progression and metabolic dysfunction. Next the investigators would like to determine the shift in the muscle secretory activity induced by regular exercise intervention, which the investigators think could be translated into the beneficial changes in clinical phenotypes, determined by neuroimaging, cognitive function tests and metabolic phenotyping.
Primary outcomes
- muscle microRNAs and myokines
- whole body energy metabolism
- cognitive function
- motoric function
History
Last registry update
Study completion
Primary completion
Started
Registered