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No phaseCompletedAge-related condition

Finnish Vitamin D Trial (FIND)

Sponsor
University of Eastern Finland (Academic or other)
Enrollment
2,495 enrolled
Conditions
Cardiovascular Diseases; Cancer
Interventions
Vitamin D3; Vitamin D3; Placebo
Ages
adults, older adults
Registry
NCT01463813

Full record on ClinicalTrials.gov

From the registry

The Finnish Vitamin D Trial (FIND) is a randomized, double-blind, placebo-controlled, 5-year supplementation study of the benefits and risks of vitamin D in the primary prevention of cardiovascular (CVD) and cancer among 18000 men 60 years or older and women 65 years or older. \[Edit 25.3.2015: Due to difficulties in recruitment and funding, the study size is approximately 2500 subjects, with a 550 subject subgroup with more detailed examinations\] The participants will be randomized to 3 groups with 6000 in each, with daily supplementation of either: 1) 40 µg/day (1600 IU) of vitamin D3, 2) 80 µg/day (3200 IU) of vitamin D3, or 3) placebo. \[Edit 15.3.2015: The 2500 subjects are randomized in 3 groups, approximately 830 subjects per group.\] Compliance, use of non-study drugs or supplements, diet, development of endpoints, and CVD and cancer risk factors will be assessed by questionnaires. Blood samples will be collected for assessment of effect modification by baseline 25-hydroxyvitamin D, as well as for future ancillary studies of genetic/biochemical hypotheses. Event data…

Primary outcomes

  • Cardiovascular disease
  • Cancer

History

  1. Last registry update

  2. Primary completion

  3. Started

  4. Registered

Papers citing this trial