Early phase 1Status unknownAge-related condition
The mechanism of delirium induced by ICAM-1-mediated transportation of hepatic exosomal miR-122 into brain following liver surgery and application study
- Sponsor
- Jiangsu Province Hospital (The First Affiliated Hospital with Nanjing Medical University)
- Enrollment
- 230 planned
- Conditions
- Postoperative delirium (POD) commonly occurs in elderly patients 2 to 5 days after anesthesia and surgery, with the primary clinical manifestation being acute, fluctuating impairment of attention and ; the overall incidence of POD in patients aged 65 years and older is approximately 12%, and it increases gradually with age. Notably
- Interventions
- Normal saline; Dexmedetomidine
- Ages
- older adults
- Registry
- ChiCTR2600131498
Full record on the Chinese Clinical Trial RegistrySource: WHO ICTRP, processed September 7, 2026
Primary outcomes
- Assessment of Postoperative Delirium;
History
Started
Last registry update
Registered