Bone
LncRNA H19 loss impairs osteoblast differentiation in cells
Knocking down the long non-coding RNA H19 inhibited pre-osteoblast differentiation without triggering senescence, while its overexpression promoted calvarial defect…Knocking down the long non-coding RNA H19 inhibited pre-osteoblast differentiation without triggering senescence, while its overexpression promoted calvarial defect repair in mice.
Experiments in mouse cellsStem cell differentiation