Syntara

CompanyAustralia

Syntara develops 3 assets, the furthest in phase 2 (Amsulostat in myelofibrosis). Mostly small molecule acting on inflammation, LOX and LOXL1; based in Australia.

3
Assets
Furthest
Phase 2
3
Trials
0
Signals

Pipeline

3
  • Amsulostat

    Inhibits lysyl oxidase family enzymes to prevent collagen cross-linking and fibrosis.

    Phase 2, Small molecule, LOX, LOXL1, myelofibrosis

  • PXS-4728A

    Inhibitor of SSAO/VAP-1 (and AOC3) reducing neuroinflammation and microglial activation

    Phase 2, Small molecule, Inflammation, AOC3, REM sleep behavior disorder

  • TPI 1020

    Nitric oxide-donating derivative of budesonide with anti-inflammatory activity

    Phase 2, Small molecule, NR3C1, Inflammation, copd bronchitis

Full company profiles: pipeline, trials, funding and people.

See Pro

In the full profile

  • Evidence behind the mechanisms3
  • Trials3
  • Similar companies6

Updated 7 Oct 2026 · 7 sources

Intelligence