No phaseNot yet recruiting
Functional Foods for Health
Assessing the Effects of a Novel Seaweed-containing Functional Food Product on Stress-Associated Immune and Gut Health Outcomes
- Sponsor
- University of Reading (Academic or other)
- Enrollment
- 40 planned
- Conditions
- Stress, Psychological
- Interventions
- Sodium alginate; Placebo (maltodextrin)
- Ages
- adults
- Registry
- NCT07871682
Full record on ClinicalTrials.gov
From the registry
The gut plays an important role in supporting the immune system, and certain dietary components such as probiotics (beneficial bacteria) and prebiotics (fibres that feed beneficial bacteria) can help to maintain gut and immune health. Alginate is a natural fibre extracted from brown seaweed that is widely used in foods which may help support beneficial gut bacteria and regulate inflammation. Ongoing psychological stress is known to affect immune function and increase inflammation in the body. This study will investigate whether a daily jelly containing alginate support gut health and improve immune responses compared to a placebo in adults experiencing higher levels of chronic stress. We are recruiting participants with elevated chronic stress to assess whether a functional jelly containing alginate, can help to reduce markers of inflammation, by mediating a change in gut microbiota composition.
Primary outcomes
- Difference in plasma interleukin-6 (IL-6) concentration between alginate intervention and placebo after 28 days
History
Primary completion expected
Started
Registered