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Obesity and Clinical and Cytokine Responses to Periodontal Therapy

Evaluation of Biochemical and Periodontal Parameters in Obese Individuals

Sponsor
Emine Çifcibaşı (Academic or other)
Enrolment
80 enrolled
Conditions
Periodontitis; Obesity (Body Mass Index >30 kg/m2)
Interventions
Scaling and Root Planing (SRP)
Ages
adults
Registry
NCT07869277

Full record on ClinicalTrials.gov

From the registry

This prospective controlled clinical study included 80 participants allocated into four groups according to body mass index (BMI) and periodontal status: obese periodontitis, normal-weight periodontitis, obese periodontally healthy, and normal-weight periodontally healthy. Clinical periodontal parameters and salivary levels of IL-6, IL-10, TNF-α, and adiponectin were assessed at baseline in all participants. Individuals with periodontitis received non-surgical periodontal therapy, and clinical and biochemical evaluations were repeated after 3 months.

Primary outcomes

  • Change in Probing Pocket Depth (PPD) After Non-Surgical Periodontal Therapy
  • Change in Clinical Attachment Level (CAL) After Non-Surgical Periodontal Therapy

History

  1. Registered

  2. Study completion

  3. Primary completion

  4. Started