No phaseStatus unknownHealthspan endpoint
Anaesthetic Depth and Short Term Delirium Post Cardiac Surgery Intervention (BISCAR)
- Sponsor
- Centre Cardiologique du Nord (Academic or other)
- Enrollment
- 200 planned
- Conditions
- Post-operative Delirium; Anaesthetic Depth
- Interventions
- General anesthesia with propofol or sevoflurane; CAM-ICU (Confusion Assesment Method ICU) at day 3 post-operative
- Ages
- older adults
- Registry
- NCT05877326
Full record on ClinicalTrials.gov
From the registry
Postoperative delirium (POD) is a critical complication of major surgery and affects up to 70% of surgical patients over the age of 60 years. The additional healthcare costs associated with delirium exceed €50,000 per patient per year due to prolonged hospital stay, increased risk of long-term care or institutionalization, and the risk of developing dementia or cognitive impairment . Therefore, prevention of POD is a major goal in the perioperative setting. The investigator proposes this randomized study to evaluate the interest of a reduced anesthetic depth to prevent short-term cognitive disorders after cardiac surgery in elderly subjects. Method: Patients over 75 years old scheduled to undergo one of the cardiac surgeries of interest (valvular, coronary bypass, aortic or combined surgery) will be randomized to 2 paralell arms : * Perioperative anesthesia with a BIS (Bispectral index) target of 35 * Perioperative anesthesia with a BIS(Bispectral index) target of 55 The presence of mental confusion will be determined by CAM-ICU ( Confusion Assessment Method for the ICU ) at…
Primary outcomes
- To demonstrate the benefit of reduced depth of anesthesia
History
Primary completion
Started
Last registry update
Registered