Chinese Journal of Natural Medicines
Icariin eases cognitive deficits and inflammation in mice
In APP/PS1 mice and cultured microglia, the compound promoted PINK1-related mitophagy and suppressed NLRP3- and GSDMD-mediated inflammatory injury.In APP/PS1 mice and cultured microglia, the compound promoted PINK1-related mitophagy and suppressed NLRP3- and GSDMD-mediated inflammatory injury.
Experiments in miceInterventions