bioRxiv
Single-neuron sequencing reveals widespread low-frequency somatic mutations in dementia brains
Human neurons from frontotemporal lobar degeneration patients showed ultra-low-frequency TARDBP variants that were less abundant in individuals who died at older ages.Human neurons from frontotemporal lobar degeneration patients showed ultra-low-frequency TARDBP variants that were less abundant in individuals who died at older ages.
Preprint: case-control study in peopleMechanisms