Translational Psychiatry·16 SepRegional juxtacortical microstructural changes and gene expression provide insights into neurodegeneration in Alzheimer's diseaseStudy in peopleMechanismsPaper
Drugs·1 SepPlasma Biomarker Effects of Oral Valiltramiprosate/ALZ-801 in Early Alzheimer's Disease from Phase 3 and Phase 2 Trials: Analysis of Core Biomarkers and Correlations with Clinical and Neuroimaging OutcomesTrial in peopleInterventionsPaper
AAIC 2025 Abstract·8 JanUncovering Lipid Biomarkers Linked to Methylphenidate Efficacy in Treating Apathy in Alzheimer's Disease: Insights from the ADMET 2 trialTrial in peopleBiomarkersPaper
AAIC 2025 Abstract·26 DecTargeting SEMA4D/PLXN signaling through reactive glia as a common pathology for the treatment of neurodegenerative disordersTrial in peopleInterventionsPaper
AAIC 2025 Abstract·26 DecCognitive Effects of Combined Aerobic Exercise and Cognitive Training in Older Adults with Mild Cognitive ImpairmentTrial in peopleInterventionsPaper
AAIC 2025 Abstract·26 DecBlood biomarkers for Alzheimer's disease are correlated with treatment outcomes in a randomized trial assessing the effects of escitalopram on agitationTrial in peopleBiomarkersPaper
AAIC 2025 Abstract·23 DecCorrelations of Valiltramiprosate Effects on Hippocampal Volume and Cortical Thickness with Clinical Outcomes in the Pre‐Specified MCI Group: Subgroup Analysis from the 78‐Week APOLLOE4 Phase 3 Trial in APOE4/4 HomozygotesTrial in peopleInterventionsPaper
AAIC 2025 Abstract·23 DecEfficacy and Safety of Oral Valiltramiprosate in APOE4/4 Homozygotes with Early AD: Topline Results from the APOLLOE4 Phase 3 TrialTrial in peopleInterventionsPaper
AAIC 2025 Abstract·23 DecValiltramiprosate Effects on Microstructural Integrity of Grey and White Matter in APOE4/4 Homozygotes with Early AD and their Correlations to Clinical Outcomes: MRI Mean Diffusivity Results from the 78‐Week APOLLOE4 Phase 3 TrialTrial in peopleInterventionsPaper
AAIC 2025 Abstract·23 DecSafety and ARIA Results of the Oral Anti‐Amyloid Agent Valiltramiprosate from the Phase 3 APOLLOE4 Trial in APOE4/4 Homozygotes with Early ADTrial in peopleInterventionsPaper