Axonal density index

Biomarker

1 paper3 findings

  • Humans1

Effects

1

Cognitive decline

downin humans1

1 study
  1. Axonal density index decreases cognitive decline in humans.

    “In the CI group, higher baseline ADI was associated with slower cognitive decline and a reduced risk of dementia.”

    Humansin cognitively impaired participants

    Axonal Health Protects Against Cognitive Decline and Dementia Risk in Prodromal Alzheimer’s Diseases

    AAIC 2025 abstract23 Dec 2025

Upstream

1

Alzheimer's disease

downin humans1

1 study
  1. Alzheimer's disease decreases axonal density index in humans.

    “The CI group exhibited lower baseline ADI and a faster rate of decline over time compared to the CN group.”

    Humansin CI vs CN groups

    Axonal Health Protects Against Cognitive Decline and Dementia Risk in Prodromal Alzheimer’s Diseases

    AAIC 2025 abstract23 Dec 2025

More on Alzheimer's disease

Associations

1

Dementia

downin humans1

1 study
  1. Axonal density index lowers the risk of dementia in humans.

    “higher baseline ADI was associated with slower cognitive decline and a reduced risk of dementia.”

    Humansin cognitively impaired participants

    Axonal Health Protects Against Cognitive Decline and Dementia Risk in Prodromal Alzheimer’s Diseases

    AAIC 2025 abstract23 Dec 2025

More on Dementia

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