EMBO Reports
Circadian E3 ligase FBXL21 regulates daily muscle proteostasis by targeting DNAJB6
Loss of FBXL21 disrupts client protein degradation, worsening stress responses in muscle cells and mutant mice.Loss of FBXL21 disrupts client protein degradation, worsening stress responses in muscle cells and mutant mice.
Experiments in miceMechanisms