Nature Biotechnology·29 AugPrecise genomic integration of large DNA fragments by donor-directed annealing using prime editingExperiments in cellsInterventionsPaper
ADA Scientific Sessions 2026 Abstract·6 JunHM17321, a Novel UCN2 Analog, Improves Weight Loss Quality in Combination with Amylin Analogs in DIO RatsExperiments in animalsInterventionsPaper
ADA Scientific Sessions 2026 Abstract·6 JunCardiorenal Protective Effects of a CRFR2-Selective UCN2 Analog, HM17321, in Spontaneously Hypertensive Rats (SHR)Experiments in animalsInterventionsPaper
ADA Scientific Sessions 2026 Abstract·5 JunHM17321, a CRFR2 Selective UCN2 Analog, Prevents Muscle Loss and Functional Decline in Sarcopenic MiceExperiments in miceSarcopeniaPaper
ADA Scientific Sessions 2025 Abstract·13 JunRobust Antiobesity Effect and Mechanistic Insights of HM15275, a Novel Long-Acting GLP-1/GIP/Glucagon Triple Agonist in Animal Model of ObesityExperiments in animalsInterventionsPaper
ADA Scientific Sessions 2025 Abstract·13 JunMetabolic Adaptation of Liver with Treatment of HM15275, a Long-Acting GLP-1/GIP/Glucagon Triple Agonist, Supporting Lean Mass PreservationExperiments in animalsInterventionsPaper