Papers by Duc M. Duong · AgingResearch.News

PNAS29 Sep
Astrocytic BAG3 regulates protein clearance systems linked to Alzheimer disease
Loss of the chaperone mediator in human astrocytes disrupts autophagy, proteasomes, and retromer traffic while impairing amyloid-beta proteostasis in neuron cocultures.Loss of the chaperone mediator in human astrocytes disrupts autophagy, proteasomes, and retromer traffic while impairing amyloid-beta proteostasis in neuron cocultures.
Experiments in human cellsMechanisms
Paper
AAIC 2025 Abstract9 Jan
Proteomic subtyping of Alzheimer's disease CSF links blood‐brain barrier dysfunction to reduced levels of tau and synaptic biomarkers
Study in peopleMechanisms
Paper
AAIC 2025 Abstract9 Jan
Plasma proteomic analysis of a biomarker‐defined subpopulation in the SHINE Ph2 trial to identify molecular correlates to the favorable decrease in the neuroinflammatory marker GFAP with zervimesine in Alzheimer's disease participants
Trial in peopleInterventions
Paper
AAIC 2025 Abstract26 Dec
Exploratory CSF proteomic analysis of a pre‐specified pTau217 subgroup from the SHINE clinical trial identifies biomarkers correlated with cognitive improvement in Alzheimer’s disease patients treated with zervimesine
Trial in peopleInterventions
Paper

AAIC 2025 Abstract23 Dec
Multi‐Omics analysis identifies that different genetic perturbations affect various molecular mechanisms underlying Alzheimer's Disease (AD) in an age‐dependent manner
Experiments in animalsMechanisms
Paper