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Orthostatic sbp decline

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: National Institute on Aging
  • Humans1

Outcomes

1

Cognitive functions

no changein humans1

1 study

  1. Orthostatic sbp decline has no effect on cognitive functions in humans.

    “There was no significant association between cognitive functions and orthostatic SBP decline at 1, 3, and 5 minutes of standing.”

    Humansotherwise healthy eldersn = 70

    Effect of blood pressure on cognitive functions in elderly persons

    The journals of gerontology. Series A, Biological sciences and medical sciences1 Nov 2004

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