Multitarget stool DNA

1. Multitarget stool DNA has no effect on aerodigestive cancer in humans (7 observed vs 7.62 expected, P = 0.823).

   “Seven patients developed aerodigestive cancers (2 pancreatic, 5 lung), consistent with expected age- and sex-adjusted Surveillance, Epidemiology, and End Results incidence (n = 7.62) ( P = 0.823).”

   Humansafter positive mt-sDNA and negative colonoscopymedian 4.4 yearsn = 328

   Negative Colonoscopy After Positive Multitarget Stool DNA: Subsequent Aerodigestive Cancer Diagnosis and Recommendations in the Community Setting

   Clinical and translational gastroenterology·17 Aug 2026

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1. Multitarget stool DNA predicts colorectal neoplasm in humans (100.0% - 43.0% and 53.3% - 27.2%).

   “mt-sDNA demonstrated superior sensitivity compared to FIT in detecting CRC (100.0% - 43.0%) and advanced adenomas (53.3% - 27.2%)”

   Reviewin samples completing both tests

   Effectiveness of multitarget stool DNA versus faecal immunochemical testing alone in detecting colorectal cancer and advanced polyps: A systematic review

   Cancer epidemiology·14 Aug 2026

More on Colorectal neoplasm