1 paper2 findings
DTI-ALPS
upin humans1
Kw is associated with DTI-ALPS in humans (β = 0.402 × 10−2, p = 0.022).
“Kw was positively associated with DTI-ALPS (β = 0.402 × 10−2, p = 0.022) and negatively associated with FW (β = -0.676 × 10−3, p = 0.008).”
Humansbrainn = 30
Brain scans suggest poorer fluid clearance in older adults
Imaging neuroscience (Cambridge, Mass.)8 Oct 2026
Older age
downin humans1
Older age is associated with Kw in humans (p = 0.021).
“Older individuals showed reduced whole-brain Kw (p = 0.021), increased white matter FW (p = 0.002), and reduced DTI-ALPS (p < 0.001) compared to younger adults.”
Humansbrainn = 30
Brain scans suggest poorer fluid clearance in older adults
Imaging neuroscience (Cambridge, Mass.)8 Oct 2026
A cross-sectional study of 30 healthy adults linked older age to brain scan measures suggesting impaired fluid clearance and altered barrier function.A cross-sectional study of 30 healthy adults linked older age to brain scan measures suggesting impaired fluid clearance and altered barrier function.