Research Square · Oct 14, 2026

Psychological, motivational, and physical effects of a supervised exercise program in women with breast cancer undergoing adjuvant treatment: a pilot intervention study

By Fresno-Alba S, Leyton-Román M, Caruana AF et al.

Background This study examined the effects of a supervised physical exercise programme on physical, psychological, and motivational outcomes in women with breast cancer receiving adjuvant treatment. Methods Sixteen participants completed a structured intervention over several weeks, assessing changes in muscle strength, functional capacity, psychological well-being, motivation to exercise, and overall quality of life. Results The results showed significant improvements in physical parameters, including increased strength and functional performance, along with reductions in anxiety and depression levels. Participants also demonstrated increased intrinsic motivation to maintain regular exercise and reported positive and significant changes in their perception of quality of life and physical well-being. Conclusion These findings suggest that incorporating individualised exercise programmes during adjuvant therapy provides multidimensional benefits, supporting physical recovery, psychological well-being, and adherence to healthy behaviours. Trial registration: ClinicalTrials.gov NCT07843121 25/09/2026). Retrospectively registered.

doi.org/10.21203/rs.3.rs-9897997/v1Open accessInterventions

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