Biomedicine / [publiee Pour L'A.A.I.C.I.G.] · Apr 1979
Adverse effects of interferon treatment on the life span of NZB mice
By Sergiescu D, Cerutti I, Efthymiou E et al.
NZB mice treated with interferon from birth and for over a year, display early some characteristics of the autoimmune disease. In these animals, mortality is clearly higher than in controls. Their death occurs 3 to 6 months before that of mice injected with a "mock" preparation.