Skip to content
A
  • HomeHome
  • SearchSearch
  • AskAsk
  • SavedSaved
  • IntelligenceIntelligence
InterventionsAnimals

The active ingredient madecassoside in Huyan no. 1 formula ameliorates D-gal-induced renal aging through the AMPK/MAPK/AP-1 signaling pathway

International Immunopharmacology

  • Madecassoside
  • Huyan no. 1
  • AMPK signalling
  • Cellular senescence
  • IL-1β
  • Mice

The paper

Huang L, Yu S, He Y et al.

International Immunopharmacology · 3 Sep 2026

doi.org/10.1016/j.intimp.2026.117339PubMed 42691527

More on Cellular senescence

  • Astragaloside IV reduces cardiac aging in mice by restoring mitochondrial balance

    FASEB Journal · 2 Oct 2026

  • Erigeron breviscapus extends lifespan in worms

    Biogerontology · 3 Oct 2026

  • Baicalein reduces disuse-driven skeletal senescence and alters gut microbes in rats

    Molecules · 2 Oct 2026

  • A distinct p21-driven macrophage senotype accumulates during aging and liver disease

    bioRxiv · 2 Oct 2026

© 2026 AgingResearch.News

PrivacyTermsContact

    News

    See all →

    Longevica finds over sixty life-extending compounds in four-year mouse screen

    CompanyLongevity.Technology

    Immune aging accelerates near ages 40 and 60

    ResearchFuturity

    Direct AMPK activation modestly lengthens lifespan in short-lived species

    ResearchFight Aging!

    A protein complex with a bound molecule sits beside an unbound complex, with slightly more intact cells beneath the bound form and more fragments beneath the…

    Trials

    See all →

    Registered6 Oct 2026

    AKG and Brain Health in Aging

    Phase 2 · University of Oklahoma

    Registered2 Oct 2026

    Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

    Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

    Registered7 Oct 2026

    AI-Based Conversational Social Support for Older Adults With Heart Failure

    Chang Gung University of Science and Technology

    Trending

    Evidence →
    1. Intervention · 66 papersExercise
    2. Gene · 24 papersAPOE
    3. Disease · 125 papersCardiovascular disease
    4. Process · 120 papersInflammation
    5. Biomarker · 46 papersBody mass index
    6. Intervention · 44 papersSmoking

    Topics

    See all →
    • Mechanisms293
    • Interventions412
    • Biomarkers387
    • Populations562
    • AI & data144
    • Industry & policy28
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News