InterventionsCells
Metformin activates the mitochondrial unfolded protein response via the AMPK/SIRT1 pathway to delay intervertebral disc degeneration
Free Radical Biology & Medicine
- Metformin
- Mitochondrial unfolded protein response
- SIRT1
- Intervertebral disc degeneration
- Mitochondrial membrane potential
- Rats
The paper
Shao S, Huang Z, Liu J et al.
Free Radical Biology & Medicine · 2 Sep 2026
