Skip to content
AgingResearch.News
  • HomeHome
  • SearchSearch
  • AskAsk
  • FollowingFollowing
  • SavedSaved
AgingResearch.News
Journal of Cellular and Molecular Medicine

The Mechanistic Study of Melatonin Regulation of p16Ink4a and Oct4 in Anti-Cellular Senescence

By Yang Xu, Cong Zhang, Li Wang, Xiaoyu Chen
Experiments in mouse cellsInterventions
Paper
  • Melatonin
  • Cellular senescence
  • VDR
  • CDKN2A
  • POU5F1
  • Mice

The paper

Yang Xu, Cong Zhang, Li Wang, Xiaoyu Chen

General Hospital of Shenyang Military Region

Journal of Cellular and Molecular Medicine, 1 Aug 2026

doi.org/10.1111/jcmm.71321PubMed 42608871

More on Cellular senescence

  • Physiological Reports·3 Oct 2026

    CD47 blockade reduces doxorubicin-induced cardiac aging in male mice

  • bioRxiv·2 Oct 2026

    A distinct p21-driven macrophage senotype accumulates during aging and liver disease

  • Pharmacological Research·2 Oct 2026

    Extracellular vesicles carrying two microRNAs reduce vascular aging markers in progeria cells

  • Bone·3 Oct 2026

    LncRNA H19 loss impairs osteoblast differentiation in cells

PrivacyTermsContact© 2026 AgingResearch.News

    News

    See all
    ER-100 glaucoma trial findings support testing higher dosesTrialsLongevity.Technology and 3 moreNew immune cell map reveals how individual immune aging trajectories divergeResearchMedical Xpress and 2 moreNewer cohorts of older Europeans show slower intrinsic capacity lossResearchThe Lancet Healthy Longevity

    Trials

    See all
    AKG and Brain Health in AgingPhase 2Registered 6 Oct 2026, University of OklahomaSafety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Phase 1Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene TechnologyAI-Based Conversational Social Support for Older Adults With Heart FailureRegistered 7 Oct 2026, Chang Gung University of Science and Technology

    Trending

    See all
    Vitamin D deficiencyDiseaseSevere vitamin D deficiency is linked to higher death rates, and 1 more story this weekKetogenic dietInterventionKetogenic diet improved heart function in aged miceNicotinamide ribosideInterventionNicotinamide riboside did not improve early Parkinson diseaseTERTGeneBlood-cell telomerase delays premature aging in zebrafishPregnancyInterventionEstimated brain-age gap rises by three years in pregnancyChildhood lonelinessInterventionChildhood loneliness linked to faster frailty progression

    Topics

    See all
    Mechanisms245Interventions419Biomarkers400Populations530AI & data162Industry & policy16
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News