PLOS Biology · May 22, 2026

Harnessing the stem cell potential in the human hippocampus to limit cognitive aging

By Mhatre S, Moore DL

The field of human adult neurogenesis has been controversial despite mounting evidence. The authors propose moving beyond debating the existence of adult neurogenesis and towards discovering strategies to harness endogenous stem cell potential for resilience against cognitive aging.

doi.org/10.1371/journal.pbio.3003787Open accessPubMed 42172195Interventions