Journal of Women's Health · Dec 30, 2025

Mental Health Issues in Women

By Nourbakhsh PS, Kransdorf LN

This Clinical Update series is intended to help providers stay up to date on important articles that have been published on topics relevant specifically to the care of women. Articles were identified by reviewing the high-impact medical and women's health journals, national guidelines, ACP JournalWise and NEJM Journal Watch. In this update on mood disorders, we have included articles pertinent to opioid use disorder, given the ongoing opioid crisis in the United States. We analyzed several interesting studies describing the role between hormones and mood disorders including menopausal hormone therapy (HT) and schizophrenia, intrauterine devices (IUDs) and depression, and menstrual cycle phase and suicidality. Lastly, we highlighted studies pertaining to the safety of buprenorphine combined with naltrexone in pregnant women.

doi.org/10.1177/15409996251408967 PubMed 41468028 Interventions