Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine] · Sep 6, 2025

The role and research progress of vitamin D in skin aging

By Bai H, Wang M, Zhao SS et al.

Skin aging is a complex physiological process that is associated with various skin diseases and affects appearance.Vitamin D, a fat-soluble vitamin synthesized after exposure of the skin to ultraviolet B radiation, has been found to regulate skin aging by modulating the physiological functions of skin cells, regulating the immune system, inducing antioxidative responses, inhibiting DNA damage, and promoting its repair. This article elucidates the multi-target mechanism of vitamin D in delaying skin aging, providing a new theoretical foundation for preventive medicine to retard aging and related diseases through nutritional intervention.

doi.org/10.3760/cma.j.cn112150-20250215-00110PubMed 40955033Interventions