Frontiers in Bioengineering and Biotechnology · Feb 12, 2025

Advances in regenerative medicine-based approaches for skin regeneration and rejuvenation

By Dutra Alves NS, Reigado GR, Santos M et al.

Significant progress has been made in regenerative medicine for skin repair and rejuvenation. This review examines core technologies including stem cell therapy, bioengineered skin substitutes, platelet-rich plasma (PRP), exosome-based therapies, and gene editing techniques like CRISPR. These methods hold promise for treating a range of conditions, from chronic wounds and burns to age-related skin changes and genetic disorders. Challenges remain in optimizing these therapies for broader accessibility and ensuring long-term safety and efficacy.

doi.org/10.3389/fbioe.2025.1527854 Open access PubMed 40013305 Interventions