Ageing Research Reviews · Feb 20, 2017

Protective effects of short-term dietary restriction in surgical stress and chemotherapy

By Brandhorst S, Harputlugil E, Mitchell JR et al.

Reduced caloric intake including fasting, as well as the dietary composition or the timing of food intake, impact longevity, likely through a modification in the onset or the severity of chronic aging-related diseases such as cancer. As with pre- and post-operative dietary recommendations, evidence-based nutritional advice from healthcare professionals during and after cancer treatment is often vague or conflicting. We hypothesize that preventive dietary recommendations can help in the context of both chronic cancer treatment efficacy and the avoidance of development of secondary malignancies, as well as in the context of protection from the acute stress of surgery. In this perspective review, we will discuss the latest findings on the potential role of short-term dietary restriction in cancer treatment and improvement of surgical outcome.

doi.org/10.1016/j.arr.2017.02.001PubMed 28216454Interventions