Advances in Gerontology · 2014
Rat tissues antioxidant status correction by peptide delta sleep during physiological aging of the organism
By Bondarenko TI, Kutilin DS, Mikhaleva II
It is shown that exogenous delta-sleep inducing peptide increases glutathione antioxidant system level in rat tissues at different stages of ontogenesis, by subcutaneous injection to rats 2-24 months postnatal development in a dose of 100 mg/kg animal body weight by courses of 5 consecutive days per month, and this effect is especially marked in non-renewable postmitotic tissues.