Revue Medicale Suisse · Mar 28, 2007
Androgen deficiency in women: indication and risks of testosterone or DHEA treatment
By Martin-Du Pan R
Androgen deficiency syndrome is defined by impaired well being and libido in women with adequate estrogenization and low levels of total serum testosterone (T). The causes of low T levels are discussed. Seven placebo controlled studies have shown that percutaneous administration of T is able to increase sexual activity and libido in ovariectomized women (5 studies), after hypophysectomy and in natural menopause. DHEA (50 mg/d) is beneficial only in women with Addison disease or after hypophysectomy but not in natural adrenopause. Other beneficial and side effects of androgenotherapy are discussed in particular the breast cancer risk.