Bulletin of Experimental Biology and Medicine · Mar 2001
Immunohistochemical and morphometric analysis of effects of vilon and epithalon on functional morphology of radiosensitive organs
By Khavinson VK, Yuzhakov VV, Kvetnoi IM et al.
Studies of the effects of vilon and epithalon on functional morphology of the thymus, spleen, and duodenum in intact rats and rats exposed to single whole-body gamma-irradiation in a dose of 6 Gy showed that vilon stimulated proliferative activity of thymocytes and enhanced proliferative potential of stem cells in the intestine, thus stimulating the postradiation recovery of critical organs. Epithalon decelerated metabolic processes in the duodenal mucosa and suppressed hemopoiesis and lymphopoiesis in the spleen.