Revista Chilena de Rehabilitación y Actividad Física · Aug 10, 2026
Effects of multicomponent training on psychological and behavioral symptoms and functional status in a person with Alzheimer's disease residing in an island region: a single-case study
By Molina JS, Sánchez CEZ
Psychological and behavioral symptoms are common in patients diagnosed with dementia, especially Alzheimer's disease (AD), leading to functional impairments. Previous studies evaluating the effects of multicomponent training on these psychological and behavioral symptoms are inconsistent. Objective: To evaluate the effect of a multicomponent physical training program on the psychological and behavioral symptoms (PBS) and functional status of a person with Alzheimer's disease residing in an island region. Method: A single-case study (N=1) was conducted with an 84-year-old woman diagnosed with Alzheimer's disease and clinically significant psychological and behavioral symptoms. The intervention consisted of 30- to 45-minute sessions combining aerobic, muscle-strengthening, and balance exercises. The Neuropsychiatric Inventory (NPI) was used to assess symptoms, and the Activities of Daily Living Questionnaire (ADLQ) was used to assess functional status. Results: A reduction in caregiver distress and a decrease in caregiver burden were observed. The depression and anxiety domains showed the greatest reduction; irritability decreased, and functionality in Activities of Daily Living (ADLs) and functional capacity remained stable. Conclusion: Multicomponent physical training is a viable and effective non-pharmacological technique that can reduce caregiver distress and caregiver burden in people with Alzheimer's disease. This study presents a promising alternative for reducing caregiver distress and maintaining functional capacity.