AAIC 2025 Abstract
Antiviral therapy: Valacyclovir Treatment of Alzheimer's Disease (VALAD) Clinical Trial
By Davangere P. Devanand, Thomas Wısnıewskı, Qolamreza Ray Razlighi, Show 5 more authorsEdward D. Huey
Trial in peopleInterventions
Abstract
Background: Infections may be etiologic or contribute to Alzheimer’s disease (AD) pathology. Evidence from neuroscience, epidemiology, and electronic health records data implicates herpes simplex viruses in AD, but controlled clinical trials of anti‐herpetic drugs have not been conducted. Method: In 120 participants at 3 U.S.
