InterventionsReview
Effect of the ApoE genotype on the efficacy of multidomain lifestyle interventions on cognitive change: a meta‐analysis of three randomized clinical trials
AAIC 2025 Abstract
Abstract
Background: The apolipoprotein E (ApoE) ε4 allele is the main genetic risk factor for sporadic Alzheimer's Disease and carriers are thus a key target group for prevention. ApoE genotype may also modify the association between lifestyle and cognitive impairment.
The paper
Jenni Lehtisalo, Alina Solomon, Christelle Cantet, Miia Kivipelto
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Nicola Coley, Esko Levälahti, Francesca Mangialasche, Tiia Ngandu, Sandrine Andrieu, Hidenori Arai,University of Eastern Finland · Karolinska University Hospital
AAIC 2025 Abstract · 23 Dec 2025 · CC BY
Presented at AAIC 2025
