Inflammation clinical trial in mild to moderate Alzheimer's disease: TSPO‐PET results

Abstract

Background: Brain inflammation can be assessed using translocator protein (TSPO) PET because TSPO is highly expressed by microglia, peripherally‐derived macrophages, and astrocytes. However, TSPO PET cannot differentiate between M1 (neurotoxic) and M2 (neuroprotective) microglial phenotypes.

The paper