Gan to Kagaku Ryoho Cancer & Chemotherapy · Apr 2026
Pancreaticoduodenectomy for Ampullary Carcinoma in a Patient with Dynapenia - A Case Report
By Koizumi A, Arikawa Y, Kinugasa S et al.
A 79-year-old female patient with dynapenia was diagnosed with duodenal ampullary cancer (cT1a, cN0, cM0, cStage Ⅰ) and underwent pancreaticoduodenectomy. Postoperatively, she experienced complications, a decline in her ability to perform activities of daily living and required long-term hospitalization. Dynapenia is defined as an age-related decline in muscle strength that occurs before the loss of muscle mass. In contrast, sarcopenia refers to the age-related loss of muscle or lean mass. Both conditions contribute to the decline of active and healthy aging. Dynapenia plays a significant role in the loss of physical function and increased risk of postoperative complications in highly invasive surgery like pancreaticoduodenectomy.