Archives of Physical Medicine and Rehabilitation · Jan 23, 2026

Association Between Mobility as a Time-Dependent Exposure Factor and Risk of Fall: A Retrospective Cohort Study of Older Patients With Orthopedic Conditions in a Subacute Rehabilitation Setting

By Matsuzaki H, Fukuda T, Furukawa D et al.

OBJECTIVE: To examine the frequency of falls during recovery in older patients with orthopedic conditions in a subacute rehabilitation setting and to evaluate the association between mobility and fall risk. DESIGN: Observational retrospective cohort study. SETTING: Single subacute rehabilitation hospital. PARTICIPANTS: Patients with orthopedic conditions (n=845) aged ≥65 years admitted between April 1, 2023, and November 30, 2024. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Incidence of first fall after admission. RESULTS: Of the 845 participants, 65 (7.7%) experienced a fall during follow-up (median: 42d; interquartile range, 23-64d). The fall rate per 1000 person-days increased immediately after admission, peaking at 2.41 during weeks 5-6, then declining. The Cox proportional hazards model assessing the association between mobility and fall risk showed no significant difference based on mobility at admission. However, repeated assessments showed a significantly higher hazard ratio (2.65; 95% CI, 1.16-6.04) during light assistance or supervision, defined as requiring minimal physical contact or supervision by a caregiver, compared with independent status. CONCLUSIONS: Repeated assessments of mobility as a time-dependent exposure factor revealed that fall risk was highest during periods requiring light assistance or supervision and was most frequent during weeks 5-6 of the subacute rehabilitation setting. These findings indicate that evaluating mobility only at admission is inadequate for assessing fall risk, underscoring the importance of continuous reassessment throughout the subacute rehabilitation.

doi.org/10.1016/j.apmr.2026.01.012PubMed 41581543Biomarkers

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