Aging & Mental Health · Sep 2, 2025

Psychometric evaluation of the Persian version of the mild behavioral impairment checklist (MBI-C) among the older population

By Rashedi V, Shariati B, Chehrehnegar N et al.

OBJECTIVES: Early detection of neuropsychiatric symptoms is critical for timely intervention in cognitive decline. Mild Behavioral Impairment (MBI) represents late-life behavioral changes preceding or accompanying neurodegenerative processes. This study aimed to translate, culturally adapt, and psychometrically validate the Persian version of the Mild Behavioral Impairment Checklist (MBI-C) in older Iranian adults. METHOD: A cross-sectional study was conducted among 97 participants aged ≥55 years, recruited from outpatient clinics and hospitals in Tehran. Based on DSM-5 criteria, participants were classified into Alzheimer's disease (AD), mild cognitive impairment (MCI), and cognitively healthy controls. The MBI-C was translated through standardized forward-backward methods and expert review. Cognitive status and depressive symptoms were assessed with the Abbreviated Mental Test score (AMTs) and Geriatric Depression Scale (GDS-15). RESULTS: The Persian MBI-C showed excellent internal consistency (Cronbach's α = 0.89) and satisfactory reliability across five domains. MBI-C scores differed significantly across diagnostic groups (p < 0.001), negatively correlated with AMTs, and positively correlated with GDS scores (p < 0.001). ROC analysis indicated strong diagnostic accuracy for AD (AUC = 0.83) and good accuracy for MCI (AUC = 0.72). CONCLUSION: The Persian MBI-C is a reliable and valid tool for assessing behavioral symptoms in older adults. Its clinical and research applicability is supported, with future studies needed to confirm predictive validity.

doi.org/10.1080/13607863.2025.2553321PubMed 40891668Biomarkers