Associations between depressive symptoms and subjective cognitive decline among diverse Hispanics/Latinos: Results from the study of Latinos-investigation of Neurocognitive Aging (SOL-INCA)

INTRODUCTION: Depressive symptoms and subjective cognitive decline (SCD) are commonly reported prior to cognitive impairment. We examined associations between depressive symptoms and SCD among diverse Hispanic/Latino adults to better understand how depressive symptoms should be considered when interpreting SCD. METHODS: This cross-sectional study utilized data from Hispanic/Latino adults [n = 6189; Age: M= 63.4 years, SD= 8.2; 55 % female; 40.5 % reported more than high school education] from the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA). RESULTS: Higher depressive symptoms were associated with worse global (β=0.37, SE=0.02) and domain-specific SCD (Memory: β=0.32, SE=0.02; Visual-Spatial Planning: β=0.27, SE=0.02; Executive Function: β=0.34, SE=0.02; ps < 0.001). These associations were significantly stronger for individuals with low cognitive status and current cognitive worry. DISCUSSION: These findings underscore the importance of assessing depressive symptoms in relation to SCD among diverse Hispanics/Latinos, especially among individuals with current cognitive worry and suspected cognitive impairment.