Trends in Cell Biology · Sep 23, 2020
Cellular Senescence Variation by Metabolic and Epigenomic Remodeling
By Nakao M, Tanaka H, Koga T
Cellular senescence is a state of permanent cell cycle arrest accompanied by unique secretory actions, which influences tissue formation, tumor suppression and aging in vivo. Recent evidences suggest that metabolic and epigenomic reprogram cooperatively creates phenotypic differences of senescent cells, which may provide new clues to control aging processes.