Revue Neurologique · Mar 27, 2020

Imaging of the aging brain and development of MRI signal abnormalities

By Chabriat H, Jouvent E

Major changes occur at the cerebral level with aging. Cerebral atrophy develops progressively. Multiple lesions related to small-vessel diseases are detected in association with cerebral atrophy including white-matter hyperintensities, lacunes, microbleeds, dilated perivascular spaces and cerebral, including cortex, atrophy. The clinical impact and predictive value of these Imaging makers were examined.

doi.org/10.1016/j.neurol.2019.12.009Open access, accepted manuscriptPubMed 32229042Biomarkers