Aging Clinical and Experimental Research · Nov 7, 2018

Cut-off for the Life-Space Assessment in persons with cognitive impairment

By Ullrich P, Werner C, Eckert T et al.

BACKGROUND: A version of the Life-Space Assessment in persons with cognitive impairment (LSA-CI) has recently been developed. AIMS: To establish a cut-off value for the newly developed Life-Space Assessment in persons with cognitive impairment (LSA-CI). METHODS: In a cross-sectional study including 118 multimorbid, older persons with cognitive impairment, life-space mobility (LSM) was documented by the LSA-CI. The analysis was rationalized by Global Positioning System (GPS)-based measures of spatial distance from home. A receiver-operating characteristic (ROC) curve was created and the cut-off point for the LSA-CI was identified with the Youden's Index. RESULTS: ROC curve analysis indicated a critical value of 26.75 (within a range of 0-90) to differentiate between low and high LSM with a sensitivity of 78.1% and specificity of 84.2%. DISCUSSION: Diagnostic interpretation of the ROC curves revealed that low and high LSM groups can be differentiated with the proposed cut-off. CONCLUSIONS: The proposed LSA-CI cut-off score can be recommended to tailor clinical interventions and evaluate change over time.

doi.org/10.1007/s40520-018-1062-2Open accessPubMed 30406358Biomarkers