Injury · Jun 2016

Bone mechanical properties and changes with osteoporosis

By Osterhoff G, Morgan EF, Shefelbine SJ et al.

This review will define the role of collagen and within-bone heterogeneity and elaborate the importance of trabecular and cortical architecture with regard to their effect on the mechanical strength of bone. For each of these factors, the changes seen with osteoporosis and ageing will be described and how they can compromise strength and eventually lead to bone fragility.

doi.org/10.1016/s0020-1383(16)47003-8Open access, accepted manuscriptPubMed 27338221Mechanisms