Cell Metabolism · Jun 14, 2016

Why NAD(+) Declines during Aging: It's Destroyed

By Schultz MB, Sinclair DA

NAD(+) is required not only for life but for a long life. In this issue, Camacho-Pereira et al. (2016) implicate CD38 in the decline of NAD(+) during aging, with implications for combating age-related diseases.

doi.org/10.1016/j.cmet.2016.05.022Open accessPubMed 27304496Mechanisms