British Journal of Cancer · Feb 12, 2007

Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study

By van den Brandt PA, Smits KM, Goldbohm RA et al.

Energy-adjusted magnesium intake was nonsignificantly inversely related to risk of colorectal cancer (n=2328) in the Netherlands Cohort Study on Diet and Cancer that started in 1986 (n=58 279 men and 62 573 women). Statistically significant inverse trends in risk were observed in overweight subjects for colon and proximal colon cancer across increasing quintiles of magnesium uptake (P-trend, 0.05 and 0.02, respectively). Although an overall protective effect was not afforded, our results suggest an effect of magnesium in overweight subjects, possibly through decreasing insulin resistance.

doi.org/10.1038/sj.bjc.6603577Open accessPubMed 17285123Populations