Mètode · May 13, 2026

Epigenetic clocks

By Esteller M, Santos-Pujol E

Aging is the main risk factor for diseases with high morbidity and mortality in developed countries, such as cardiovascular diseases or cancer. This process of progressive deterioration over time is associated with epigenetic drift, which consists of changes in the chemical marks on DNA that alter gene expression and contribute to the progression of decline. This progression entails an increase in biological age, understood as a person's physiological state. In this context, epigenetic clocks emerge as a key instrument for predicting a person's biological age and risk of death. In this article, we describe this useful bioinformatics tool and present its great potential in future biomedical research.

doi.org/10.7203/metode.16.32027Open accessBiomarkers

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