Vietnam Journal of Diabetes and Endocrinology · Apr 23, 2026
Study of dyslipidemia in overweight and obese patients with prediabetes
By Cao QH, Trần TN, Trần QN et al.
Objectives: To assess the prevalence of dyslipidemia and its associations with several factors: BMI, waist circumference, physical activity, and blood pressure among overweight and obese patients with prediabetes. Materials and Methods: A descriptive cross-sectional study of 104 overweight or obese prediabetic patients was conducted at the Department of General Internal Medicine–Geriatrics, Hue Central Hospital, from June 2020 to August 2022. Results: The overall prevalence of dyslipidemia was 83.7%, with elevated LDL-C being the most frequent abnormality (76.0%). The prevalence of dyslipidemia in patients with impaired fasting glucose was 1.7 times higher than in those without impaired fasting glucose. Patients with impaired glucose tolerance had a 1.9-fold higher prevalence of dyslipidemia than those without impaired glucose tolerance. Obese patients had twice the risk of elevated LDL-C compared with overweight patients. Patients with increased waist circumference had a 1.6-fold higher risk of hypertriglyceridemia and a 6.6-fold higher risk of low HDL-C than those without increased waist circumference. Physically inactive patients had a twofold higher risk of dyslipidemia and a 1.3-fold higher risk of elevated LDL-C than physically active patients. Hypertensive patients had a 3.6-fold higher risk of dyslipidemia and a 1.2-fold higher risk of elevated LDL-C compared with non-hypertensive patients. Conclusions: The prevalence of dyslipidemia among overweight and obese patients with prediabetes was very high, predominantly driven by elevated LDL-C. Obesity, increased waist circumference, physical inactivity, and hypertension were associated with a higher risk of dyslipidemia in this population.