AHA Scientific Sessions 2026 Abstract · Nov 2, 2026
Burden of Hypertensive Heart Disease Attributable to Obesity from 1990-2023. Insights from Global Burden of Disease Database
By Shahab SH, Salman Hassan SM, Saleem NUA et al.
Introduction: The rising prevalence of obesity has contributed to worsening cardiovascular health outcomes, particularly among individuals with hypertensive heart disease (HHD). Globally, populations across all SDI regions bear a substantial burden of HHD due to high rates of obesity. Methods: We conducted a population-based analysis by data from the Global Burden of Disease (GBD) 1990-2023 study to evaluate the burden of hypertensive heart disease (HHD) attributable to obesity across different SDI regions. The study calculated age-standardized incidence rates (ASIR), age-standardized prevalence rates (ASPR), age-standardized death rates (ASDR), DALYs per 100,000 population, and absolute HHD-related deaths for each year from 1990 to 2023. Results: In 2023, HHD due to obesity in High SDI regions accounted for an estimated 102,546 deaths in males (95% UI: 66,496-130,475) and 139,638 deaths in females (95% UI: 60,447-214,053) , resulting in a total of 2,237,875 DALYs in males (95% UI: 1,727,248-2,646,401) and 2,204,731 DALYs in females (95% UI: 1,371,647-3,029,215) . The age-standardized DALY rate in High SDI regions showed relative stability over the study period. The ASR-DALY per 100,000 population was 102.83 (95% UI: 76.45-125.65) in 2023, compared to 108.71 (95% UI: 80.91-135.84) in 1990, indicating a slight decrease in population-adjusted health loss over the past three decades. Similarly, in High-middle SDI regions , HHD due to obesity resulted in 48,922 deaths in males (95% UI: 30,137-67,905) and 71,719 deaths in females (95% UI: 43,097-107,362) in 2023, with corresponding DALYs of 1,156,134 in males (95% UI: 812,929-1,555,525) and 1,428,139 in females (95% UI: 981,366-2,005,067) . The ASR-DALY was 128.43 per 100,000 population (95% UI: 91.14-167.39) in 2023, reflecting a modest increase compared to 182.52 per 100,000 (95% UI: 116.10-261.42) in 1990.In Middle SDI regions , the death toll reached 37,570 in males (95% UI: 24,715-53,607) and 51,221 in females (95% UI: 31,262-77,039) , with 1,009,613 DALYs in males (95% UI: 708,324-1,428,265) and 1,199,977 DALYs in females (95% UI: 760,798-1,790,896) . The age-standardized DALY rate was 245.30 per 100,000 population (95% UI: 176.42-322.83) in 2023, compared to 193.83 per 100,000 (95% UI: 127.80-266.43) in 1990, indicating a rising population-adjusted health burden. In Low-middle SDI regions , HHD due to obesity accounted for 27,734 deaths in males (95% UI: 16,440-40,705) and 39,096 deaths in females (95% UI: 21,226-66,139) in 2023, resulting in 744,954 DALYs in males (95% UI: 471,526-1,121,881) and 924,274 DALYs in females (95% UI: 513,712-1,532,281) . The ASR-DALY was 174.76 per 100,000 population (95% UI: 117.21-256.98) in 2023, up from 104.88 per 100,000 (95% UI: 64.34-159.41) Conclusion: HHD due to obesity remains a significant public health burden across SDI regions