BiomarkersHumans
Capturing Alzheimer’s Disease Heterogeneity With Spatially Independent Patterns of Amyloid Accumulation
AAIC 2025 Abstract
Abstract
Background: Current Alzheimer’s disease (AD) research and clinical trials generally assume a single trajectory of cortical amyloid beta (Aβ) accumulation, but amyloid positron emission tomography (PET) studies suggest multiple trajectories.
The paper
Leonard Pieperhoff, Luigi Lorenzini, Mario Tranfa, Alle Meije Wink
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Prithvi Arunachalam, Craig Ritchie, Mercè Boada, Marta Marquié, Wiesje M. van der Flier, Rik R. Vandenberghe, Bernard Jimmy Hanseeuw, Pablo Martínez‐Lage, Pierre Payoux, Pieter Jelle Visser, Michael Schöll, Giovanni Battista Frisoni, Andrew Wills Stephens, Christopher Buckley, Gill Farrar, Frank Jessen, Juan Domingo Gispert, Henk J. M. M. Mutsaerts, Tiago Gil Oliveira, Lyduine Eisa Collij, Frederik Barkhof,Amsterdam University Medical Centers
AAIC 2025 Abstract · 23 Dec 2025 · CC BY
Presented at AAIC 2025
